Welcome!
ALERT ATTENTION ⚠️️
Maintenance has been scheduled for iLab Primary U.S. on June 13, 2026 at 3:30PM (UTC). During this time, the iLab platform will be inaccessible or limited in functionality. Details and updates can be found on the Agilent Status Page.
For additional information, please contact the Agilent iLab Support at ilabsupport@agilent.com.
BIO-VITAL
The Batia and Idan Ofer Center for Validation of Interventions Targeting Aging and Longevity at Einstein (BIO-VITAL) was created to accelerate the resolution of current rate-limiting steps in developing drugs that target aging.
Preclinical Aging Models Core
The Preclinical Aging Models Core (PAMC) offers access to a propriety mouse model to evaluate human aging. An extensively validated approach allows PAMC to precisely monitor the animal model lifespan and measure the impact of an intervention, by measuring stamina, coordination, memory, and metabolism.
PAMC can create a custom preclinical workflow to measure:
Cellular Aging & Technology Core
The Cellular Aging and Technology Core (CATC) provides resources to conduct research on cellular drivers of aging, specifically autophagy, proteostasis, senescence, and mitochondria function. In addition to offering a range of assays, reagents, and samples, CATC provides consultation on experimental design, data analysis and interpretation, and can coordinate efforts across the institute’s other cores.
CATC assays and tools are:
Assays include:
Preclinical Aging Models Core
Director: Derek M. Huffman, PhD
Cellular Aging & Technology Core
Scientific Director: Ana Maria Cuervo, MD, PhD
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Antonio Diaz |
Technician, Cellular Aging & Technology Core
|
antonio.diazcarretero@einsteinmed.edu
|
||
| Ana Maria Cuervo, MD, PhD |
Scientific Director, Cellular Aging & Technology Core
|
ana-maria.cuervo@einsteinmed.edu
|
||
| Derek M. Huffman, PhD |
Director, Preclinical Aging Models Core
|
derek.huffman@einsteinmed.edu
|
| Service list |
| ► Chronobiosis and Energetics/Metabolism of Aging (30) | |||
| Name | Description | Price | |
|---|---|---|---|
| Balance Beam | Inquire | ||
| Chronobiosis complete tissue and plasma (one set, i.e., Y-Y, Y-O, O-Y, O-O) | Inquire | ||
| Chronobiosis limited tissue request (one set, i.e., Y-Y, Y-O, O-Y, O-O) | Inquire | ||
| Chronobiosis plasma (one set, i.e., Y, Y-O, O-Y, O) ~50uL | Inquire | ||
| Chronobiosis Surgery+Housing (one set, i.e. Y-Y, Y-O, O-O) | Inquire | ||
| Chronobiosis Surgery+Housing Y-Y, Y-O, or O-O each | Inquire | ||
| Clamp assay: with radioisotope (mice) | Inquire | ||
| Clamp assay: with radioisotope (rats) | Inquire | ||
| Clamp assay: with radioisotope/C14 (mice) | Inquire | ||
| Clamp assay: with radioisotope/C14 (rats) | Inquire | ||
| Clamp assay: with radioisotope/C14 and ICV (mice) | Inquire | ||
| Clamp assay: with radioisotope/C14 and ICV (rats) | Inquire | ||
| Clamp data analysis | Inquire | ||
| Clamp surgery | Inquire | ||
| Complete dissection (weighing, fixation, freezing) | Inquire | ||
| Forced Exercise Test | Inquire | ||
| Forced Treadmill test | Inquire | ||
| Gait Analysis | Inquire | ||
| Grip Strength | Inquire | ||
| Inserting ICV or intra hypothalamic catheter | Inquire | ||
| Lipectomy | Inquire | ||
| Micro CT scan | Inquire | ||
| Mouse Metabolic Cages | Inquire | ||
| Object Placement | Inquire | ||
| Object Recognition | Inquire | ||
| Open Field | Inquire | ||
| qMR (rats or mice) | Inquire | ||
| Rat Metabolic Cages | Inquire | ||
| Rotarod | Inquire | ||
| Y Maze | Inquire | ||
| ► Proteostasis of Aging (14) | |||
| Name | Description | Price | |
| Complete Protein Turnover Analysis | Inquire | ||
| Consultation on study design, methods, interpretation | Inquire | ||
| Drug design consulting |
Computational docking setup and screening: |
Inquire | |
| Drug design consulting |
Docking analysis and data plotting: |
Inquire | |
| Em morphometric analysis of autophagic compartments*** | Inquire | ||
| KFERQ-Dendra - High content microscopy/96 well plate | Inquire | ||
| LC3 flux - immunoblot (8 conditions) | Inquire | ||
| Lysosomal compartment – Lysotracker/ 8 well | Inquire | ||
| Lysosomal markers (panel) - Immunoblot | Inquire | ||
| mCherry-GFP-LC3 High content microscopy/96 well plate | Inquire | ||
| Mitophagy - immunofluorescence colocalization/8 well | Inquire | ||
| Protein degradation (1 type sample 6 conditions with triplicates) | Inquire | ||
| Protein synthesis (4 samples with triplicates) | Inquire | ||
| Training in proteostasis analysis procedures | Inquire | ||
| Name | Price | |
|---|---|---|
