ALERT

The final week of February, 2019 (Feb. 25 - Mar 1), iLab Operations Software will be conducting an internal event and will be staffed at significantly reduced levels. iLab Support will prioritize critical issues first (i.e. issues that prevent key workflows from completing) and to escalate an issue, please add "Urgent" to the ticket/ email subject or press "1", when prompted, on the iLab Support phone (regional numbers can be found here). Regular support tickets will be monitored periodically and processed in order of submission starting March 4th, 2019. During this time, you can also refer to the iLab Help Site and iLab Status Page for site information. Please note that this will not affect standard Core Facility Operations.

Stable Isotope and Metabolomics Core

Overview

The Stable Isotope and Metabolomics Core can provide targeted and untargeted metabolite profiling of plasma or tissue, and the rate of change of substrates (flux), using stable isotopes and mass spectrometry. The core has a variety of in vitro and in vivo metabolic methodologies that can determine substrate flux dynamics and metabolite profiles at the organelle, cellular, tissue and whole body levels. In collaboration with other Diabetes Research Center cores, the application of mass spectrometric and other methodologies allows the elucidation of metabolic mechanisms underlying disorders in fuel homeostasis. The metabolic role of candidate molecules can be specifically delineated in vivo and in vitro, using a step-by-step hypothesis-driven approach in animals, cell lines and other models.

Services

  • Stable isotope substrate flux dynamics
  • Metabolite quantification and identification
  • Cellular rates of glycolysis and mitochondrial respiration using the Seahorse Biosciences Extracellular Flux Analyzer

Leadership

Director
Irwin Kurland, M.D., Ph.D.
718.678.1091
irwin.kurland@einstein.yu.edu

Operations Manager
Yunping Qiu, Ph.D.
718.678.1180
yunping.qiu@einstein.yu.edu

Location and hours of operation

Hours Location

M-F, 9-5    

Price 368

Links and Resources

  1. Core Website

Contacts

Name Role Phone Email Location
Yunping Qiu, Ph.D.
Operations Manager
 
718.678.1180
 
yunping.qiu@einstein.yu.edu
 
Price 368
 
Heather Zhao
Mass Spectrometer Operator
 
718.678.1180
 
xueqing.zhao@einstein.yu.edu
 
Price 368
 
Xueliang Du, Ph.D.
Seahorse Instructor
 
718.430.3637
 
xueliang.du@einstein.yu.edu
 
Forchheimer 529
 

Service list


Search available services: View: by category alphabetically
Metabolomic Modules (13)
Sample Prep (1)
Seahorse (8)

Available Equipment and Resources

Name Price
Seahorse Biosciences Extracellular Flux Analyzer XF24 View calendar
Seahorse Biosciences Extracellular Flux Analyzer XF96 View calendar
Seahorse Biosciences Extracellular Flux Analyzer XFe24 View calendar