Welcome!
The Stem Cell Isolation and Xenotransplantation Core advances stem cell and cell therapeutic research by providing key technological support for human stem cells FACS sorting and transplantation services to test stem cell differentiation potential in vivo.
Flow cytometry core facility:
Xeno core transplantation facility:
Establish Xenograft models from cell lines and patient samples provided by investigators. Methodologies for cell implantation include subcutaneous, intraperitoneal, intravenous (retro orbital, tail vein
routes), intra femoral, neonatal intracardiac and neonatal intra hepatic. Successfully engrafted tumors are propagated by serial transplantations or and used for further drug studies.
Evaluate in vivo efficacy of agents either alone or in combination with standard chemotherapy regimens against murine tumors, human tumor xenografts and transgenic mouse models of human cancer.
Formulated compounds for in vivo delivery using variety of commonly used vehicles and are administered by number of routes, including oral gavage, intraperitoneal, intravenous and by food and/or drinking water.
Closely work with principal investigators to determine max-tolerated dose after single dose, or repeat-dose toxicity studies in novel drug applications for cancer treatments on rodents.
Live bone marrow sampling, blood and tumor samples at multiple time points to assess engraftment ability, drug treatment efficiency.
Scientific Director
Ulrich Steidl, M.D., Ph.D.
718.430.3437
ulrich.steidl@einsteinmed.org
Technical Director
Daqian Sun, Ph.D.
718.430.3551
daqian.sun@einsteinmed.org
Swathi-Rao Narayanagari
718-430-2915
swathi-rao.n@einsteinmed.org
| Location | |
|
|
Chanin 638 A |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Daqian Sun, Ph.D. |
Technical Director
|
718-430-3551
|
daqian.sun@einsteinmed.org
|
Chanin 638 A
|
| Nicole Seate-Martin |
Administrator
|
718-678-1212
|
nicole.seatemartin@einsteinmed.org
|
Price 153A
|
| Swathi Rao Narayanagari |
Research Associate
|
718-430-2915
|
swathi-rao.n@einsteinmed.org
|
Chanin 638 A
|
| Service list |
| ► FACS (3) | |||
| Name | Description | Price | |
|---|---|---|---|
| Cell Sorting - Assisted |
Includes single cell sorting and deposition if required, customization of parameters including sorting pressure, nozzle size etc. |
Inquire | |
| Cell Sorting - Self Use | Inquire | ||
| Flow Cytometry Analysis | Inquire | ||
| ► Xenotransplantation (15) | |||
| Name | Description | Price | |
| NSG-SGM3 Mouse | Inquire | ||
| Live Bone Marrow Aspiration (BMA) | Inquire | ||
| Peripheral Blood Collection (submandibular) (PB) | Inquire | ||
| Bone Marrow Injections (BMI) | Inquire | ||
| Retro Orbital Injection (RO) | Inquire | ||
| Tail Vein (TV) | Inquire | ||
| Subcutaneous (SC) | Inquire | ||
| Intra Peritoneal (IP) | Inquire | ||
| Oral Gavage (OG) | Inquire | ||
| Intra Cardiac Injections in neonates (IC) | Inquire | ||
| Intrahepatic Injections in neonates (IH) | Inquire | ||
| Irradiation Service | Inquire | ||
| NSG Mouse | Inquire | ||
| Xenotransplantation Hourly Fee | Inquire | ||
| Xenotransplantation Training Fee | Inquire | ||
| Name | Price | |
|---|---|---|
