Welcome!
The Stem Cell Isolation, Xenotransplantation, and Diagnostics Core advances stem cell and cell therapeutic research by providing key technological support for human stem cells FACS sorting and transplantation services to test stem cell differentiation potential in vivo.
Flow cytometry core facility:
Xeno core transplantation facility:
Establish Xenograft models from cell lines and patient samples provided by investigators. Methodologies for cell implantation include subcutaneous, intraperitoneal, intravenous (retro orbital, tail vein
routes), intra femoral, neonatal intracardiac and neonatal intra hepatic. Successfully engrafted tumors are propagated by serial transplantations or and used for further drug studies.
Evaluate in vivo efficacy of agents either alone or in combination with standard chemotherapy regimens against murine tumors, human tumor xenografts and transgenic mouse models of human cancer.
Formulated compounds for in vivo delivery using variety of commonly used vehicles and are administered by number of routes, including oral gavage, intraperitoneal, intravenous and by food and/or drinking water.
Closely work with principal investigators to determine max-tolerated dose after single dose, or repeat-dose toxicity studies in novel drug applications for cancer treatments on rodents.
Live bone marrow sampling, blood and tumor samples at multiple time points to assess engraftment ability, drug treatment efficiency.
Scientific Director
Ulrich Steidl, M.D., Ph.D.
718.430.3437
ulrich.steidl@einsteinmed.edu
Technical Director
Daqian Sun, Ph.D.
718.430.3551
daqian.sun@einsteinmed.edu
Swathi-Rao Narayanagari
718-430-2915
swathi-rao.n@einsteinmed.edu
| Location | |
|
|
Chanin 638 A |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Daqian Sun, Ph.D. |
Technical Director Flow Cytometry facility
|
718-430-3551
|
daqian.sun@einsteinmed.edu
|
Chanin 638 A
|
| Francesco Barca |
Administrator
|
718-678-1212
|
francesco.barca@einsteinmed.edu
|
Price 153A
|
| Swathi Rao Narayanagari |
Technical Director Xeno facility/Staff Scientist
|
718-430-2915
|
swathi-rao.n@einsteinmed.edu
|
Chanin 638 A
|
| Colette Prophete |
Technical Director Diagnostics facility/Staff Scientist
|
718-678-1204
|
colette.prophete@einsteinmed.edu
|
Price 107/B140
|
| Service list |
| ► FACS (3) | |||
| Name | Description | Price | |
|---|---|---|---|
| Cell Sorting - Assisted |
Includes single cell sorting and deposition if required, customization of parameters including sorting pressure, nozzle size etc. |
Inquire | |
| Cell Sorting - Self Use | Inquire | ||
| Flow Cytometry Analysis | Inquire | ||
| ► SCI (2) | |||
| Name | Description | Price | |
| In vivo imaging System (Vevo 2100 ultrasound) Price Center Barrier | Inquire | ||
| LSR II - Independent Use | Inquire | ||
| ► Xenotransplantation (23) | |||
| Name | Description | Price | |
| Bone Marrow Injections (BMI) | Inquire | ||
| Cage Fee (Animal Institute) - Avg # of Cages per Day x # of Days | Inquire | ||
| Cage Separation per cage | Inquire | ||
| Genotyping Tissue | Inquire | ||
| Intra Cardiac Injections in neonates (IC) | Inquire | ||
| Intra muscular (IM) | Inquire | ||
| Intra Peritoneal (IP) | Inquire | ||
| Intrahepatic Injections in neonates (IH) | Inquire | ||
| Irradiation Service | Inquire | ||
| Live Bone Marrow Aspiration (BMA) | Inquire | ||
| NSG Mouse | Inquire | ||
| NSG-SGM3 Mouse | Inquire | ||
| Oral Gavage (OG) | Inquire | ||
| Peripheral Blood Collection (submandibular) (PB) | Inquire | ||
| Retro Orbital Injection (RO) | Inquire | ||
| SCID Mouse | Inquire | ||
| Subcutaneous (SC) | Inquire | ||
| Tagging per Cage | Inquire | ||
| Tail Vein (TV) | Inquire | ||
| Tail Vein Cannulation (TVC) | Inquire | ||
| Tissue collection | Inquire | ||
| Xenotransplantation Hourly Fee | Inquire | ||
| Xenotransplantation Training Fee | Inquire | ||
| Name | Price | |
|---|---|---|
