ALERT

The final week of February, 2019 (Feb. 25 - Mar 1), iLab Operations Software will be conducting an internal event and will be staffed at significantly reduced levels. iLab Support will prioritize critical issues first (i.e. issues that prevent key workflows from completing) and to escalate an issue, please add "Urgent" to the ticket/ email subject or press "1", when prompted, on the iLab Support phone (regional numbers can be found here). Regular support tickets will be monitored periodically and processed in order of submission starting March 4th, 2019. During this time, you can also refer to the iLab Help Site and iLab Status Page for site information. Please note that this will not affect standard Core Facility Operations.

Proteomics Core / LMAP

Overview

The Proteomics Facility, supported by the Laboratory for Macromolecular Analysis and Proteomics (LMAP), provides Einstein researchers with a comprehensive mass spectrometry resource for analysis of proteins, peptides and other selected families of biomolecules. Expert staff scientists are available to help plan and execute a successful proteomics based analysis. They also assist in data analysis, including statistics and data visualization.

Services

Protein-related studies:

  • Identification and quantification of purified proteins and/or complex proteomes (label-free, SILAC, isobaric tagging)
  • Determination of protein-protein interactions and protein-nucleic acid interactions
  • Computational determination of regulated protein pathways, complexes and other networks
  • Identification and quantification of protein post-translational modifications
  • Mapping of protein and proteome localization in the cell, in particular chromatin complexes
  • High throughput analysis (100s samples per day) of histone post-translational modifications
  • Determination of protein synthesis rate (turnover) as complementary quantitative dimension of protein abundance
  • Preliminary data analysis, including time-series statistics and assistance in biomarker selection


Other biomolecules:

  • Spatial localization of molecules by imaging (in situ) mass spectrometry
  • Confirmation of synthetic and recombinant molecules
  • High-resolution analysis of metabolites, drugs, peptides and other small molecules
  • Targeted assays and pharmacokinetics

Leadership

Interim Scientific Director
Steven C. Almo, Ph.D.

Operations Director
Edward Nieves

Location and hours of operation

Hours Location

M-F, 9-5  

  Ullmann 403

Links and Resources

  1. Proteomics Core Website

Contacts

Name Role Phone Email Location
Edward Nieves
Operations Director
 
718.430.3476
 
edward.nieves@einstein.yu.edu
 
Ullmann 403
 

Service List


Search available services: View: by category alphabetically
Archived (7)
Consultation & Training (4)
Electrophoresis (5)
Instruments (9)
Mass Spec (4)
Sample Prep (17)