Proteomics Core / LMAP

Overview

The Proteomics Facility, supported by the Laboratory for Macromolecular Analysis and Proteomics (LMAP), provides Einstein researchers with a comprehensive mass spectrometry resource for analysis of proteins, peptides and other selected families of biomolecules. Expert staff scientists are available to help plan and execute a successful proteomics based analysis. They also assist in data analysis, including statistics and data visualization.

Services

Protein-related studies:

  • Identification and quantification of purified proteins and/or complex proteomes (label-free, SILAC, isobaric tagging)
  • Determination of protein-protein interactions and protein-nucleic acid interactions
  • Computational determination of regulated protein pathways, complexes and other networks
  • Identification and quantification of protein post-translational modifications
  • Mapping of protein and proteome localization in the cell, in particular chromatin complexes
  • High throughput analysis (100s samples per day) of histone post-translational modifications
  • Determination of protein synthesis rate (turnover) as complementary quantitative dimension of protein abundance
  • Preliminary data analysis, including time-series statistics and assistance in biomarker selection


Other biomolecules:

  • Spatial localization of molecules by imaging (in situ) mass spectrometry
  • Confirmation of synthetic and recombinant molecules
  • High-resolution analysis of metabolites, drugs, peptides and other small molecules
  • Targeted assays and pharmacokinetics

Leadership

Interim Scientific Director
Steven C. Almo, Ph.D.

Operations Director
Edward Nieves

Location and hours of operation

Hours Location

M-F, 9-5  

  Ullmann 403

Links and Resources

  1. Proteomics Core Website

Contacts

Name Role Phone Email Location
Edward Nieves
Operations Director
 
718.430.3476
 
edward.nieves@einstein.yu.edu
 
Ullmann 403
 

Service List


Search available services: View: by category alphabetically
Archived (7)
Consultation & Training (4)
Electrophoresis (5)
Instruments (9)
Mass Spec (4)
Sample Prep (17)