Biomarker Analytic Research Core (BARC)

Overview of Services

Biomarkers are playing an increasingly important role in clinical and translational research, especially as we 
move toward an era of personalized medicine in both the prevention and treatment of disease. The Biomarker
Analytic Research Core (BARC) — the central laboratory for the ICTR and the Biorepository — provides sophisticated tools and expertise for Einstein and Montefiore investigators from the initial planning stage through analysis and data output. 
 
The services include
State-of-the-art mass spectrometry analysis, in particular stable isotopes, as well as research-grade
determination of lipids, and metabolic markers for a variety of human subjects and animal model projects,
High-throughput robotics for semiautomated high-quality sample preparation and analysis by immunoassay and liquid chromatography–mass spectrometry (LC/MS),
Support for novel developmental projects featuring applications of LC/MS and two-site bead-based assays,
Research-quality analysis of metabolites for human and animal samples using an Olympus AU400 autoanalyzer, and
advanced training in analytical chemistry.
 
In addition to its isotope dilution LC/MS assays, BARC has already validated and made available quantitative measurement of 25(OH) Vitamin D, testosterone, and androstenedione via LC/MS. Other dual-use assays for steroids are under development, including ultrahigh sensitivity salivary cortisol, estradiol, and progesterone which will support both clinical care and research use. BARC also offers a novel method for LC/MS measurement of C-peptide, and is currently the reference lab for an ongoing clinical trial measuring insulin secretion.
 
All samples processed are labeled with barcoded cryolabels for easy identification. Records of samples and
data are seamlessly integrated and tracked, and are remotely accessible via a secure research database.


Leadership

Scientific Director
Daniel Stein, M.D.
718.430.2446
daniel.stein@einstein.yu.edu

Scientific Director
Norman Fleischer, M.D.
718.430.3187
norman.fleischer@einstein.yu.edu

Operations Director
Nicole Bjorklund, Ph.D.
718.430.2421
nicole.bjorklund@einstein.yu.edu

 

Location and hours of operation

Hours Locations

Mon - Fri    
9 - 5

1300 Morris Park Avenue 111 East 210th Street
Bronx, NY 10461 Bronx, NY 10467

Links and Resources

  1. Our Website
  2. Assay List
  3. ICTR Services

Contacts

Name Role Phone Email Location
Daniel Stein, M.D.
Scientific Director
 
718.430.2446
 
daniel.stein@einstein.yu.edu
 

 
Norman Fleischer, M.D.
Scientific Director
 
718.430.3187
 
norman.fleischer@einstein.yu.edu
 

 
Nicole Bjorklund, Ph.D.
Operations Director
 
718.430.2421
 
nicole.bjorklund@einstein.yu.edu
 

 

Service list


Search available services: View: by category alphabetically
Sample Analysis (8)
Sample Processing (1)
Other Services (1)
Sample Processing (1)


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