Histology & Comparative Pathology Core

Overview of Services

The Histotechnology and Comparative Pathology Facility provides comprehensive histology and histopathology support to Einstein investigators and the Animal Housing and Studies Facility. The facility performs most aspects of tissue evaluation, from necropsy to the final histological diagnostic evaluation. We support quality translational research by evaluating how the genetic background, environment and sex of the animals affect the study results or gene phenotype. The goal of the facility is to provide a high-quality histology service as well as to be a resource for understanding and translating in vivo data.

Services

• Tissue preparation – fixation or freezing, decalcification and routine processing to paraffin embedding
• Full-service necropsy, histology and cryosectioning (including many special stains)
• Immunohistochemistry and enzyme histochemistry of tissue sections
• Necropsy and histopathology reports
• Rental cryostat and microtome
• Routine hematology on a variety of laboratory animal species

Leadership

Laura Ramkissoon, Operations Director

Core Staff:

Location and Hours of Operation

Hours: Monday - Friday 8:30 AM - 5:00 PM

Location: 1301 Morris Park Ave, Price Center 158, Bronx, NY  10461

Links and Resources

Internet resources

Mouse Genetics

http://www.informatics.jax.org/silverbook/contents.shtml

http://www.informatics.jax.org/

Spontaneous Diseases in Commonly Used Mouse Strains/Stocks

http://www.hopkinsmedicine.org/mcp/PHENOCORE/CoursePDFs/09s1BraytonMouseDzOutline75p.pdf

Reference for Necropsy, tissue and blood sampling, and other procedures in rodents

http://www.hopkinsmedicine.org/mcp/PHENOCORE/CoursePDFs/2013/13%20Phenocourse%20Lab%20Manual%2052p.pdf

http://www.jove.com/video/2966/diagnostic-necropsy-selected-tissue-sample-collection-rats?id=2966

Mouse Anatomy & Histology

http://www.informatics.jax.org/cookbook/

http://reni.item.fraunhofer.de/reni/trimming/

http://ntp.niehs.nih.gov/nnl/

http://www.deltagen.com/target/histologyatlas/HistologyAtlas.html

http://tvmouse.ucdavis.edu/

Mouse Embryo Atlas

http://www.emouseatlas.org/emap/home.html

Mouse Brain Resources

https://www.brain-map.org/

http://mbl.org/

Primate Diseases and Pathology

http://ocw.tufts.edu/Content/60/lecturenotes/896102

Zebrafish References

http://zfatlas.psu.edu/

http://zebrafish.org/home/guide.php

Immunohistochemistry References & Mouse Antibody Databases

http://ncifrederick.cancer.gov/rtp/lasp/phl/immuno/results.asp

Frozen Sections Trouble-Shooting

http://www.pathologyinnovations.com/new_page_3.htm

http://www.pathologyinnovations.com/frozen_block_embedding.htm

Information Resources on the Care and Welfare of Rodents

http://www.nal.usda.gov/awic/pubs/Rodents/

Cell Line Contamination

http://en.wikipedia.org/wiki/List_of_contaminated_cell_lines

Contacts