Biomarkers are playing an increasingly important role in clinical and translational research, especially as we |
move toward an era of personalized medicine in both the prevention and treatment of disease. The Biomarker |
Analytic Research Core (BARC) — the central laboratory for the ICTR and the Biorepository — provides sophisticated tools and expertise for Einstein and Montefiore investigators from the initial planning stage through analysis and data output. |
The services include |
• State-of-the-art mass spectrometry analysis, in particular stable isotopes, as well as research-grade |
determination of lipids, and metabolic markers for a variety of human subjects and animal model projects, |
• High-throughput robotics for semiautomated high-quality sample preparation and analysis by immunoassay and liquid chromatography–mass spectrometry (LC/MS), |
• Support for novel developmental projects featuring applications of LC/MS and two-site bead-based assays, |
• Research-quality analysis of metabolites for human and animal samples using an Olympus AU400 autoanalyzer, and |
• advanced training in analytical chemistry. |
In addition to its isotope dilution LC/MS assays, BARC has already validated and made available quantitative measurement of 25(OH) Vitamin D, testosterone, and androstenedione via LC/MS. Other dual-use assays for steroids are under development, including ultrahigh sensitivity salivary cortisol, estradiol, and progesterone which will support both clinical care and research use. BARC also offers a novel method for LC/MS measurement of C-peptide, and is currently the reference lab for an ongoing clinical trial measuring insulin secretion. |
All samples processed are labeled with barcoded cryolabels for easy identification. Records of samples and |
data are seamlessly integrated and tracked, and are remotely accessible via a secure research database. |
Scientific Director
Dr. Matthew Abramowitz
Matthew.Abramowitz@einsteinmed.edu
718-430-8566
Hours | Locations | ||||
Mon - Fri |
|
Name | Role | Phone | Location | |
---|---|---|---|---|
Matthew K. Abramowitz, M.D., M.S. |
Scientific Director
|
718.430.8566
|
matthew.abramowitz@einsteinmed.edu
|
|
Jeff Lafleur |
Operations Director
|
718.430.3314
|
jeff.lafleur@einsteinmed.edu
|
|
Alcia Garnett |
Technician B
|
718.430.3540
|
alcia.garnett@einsteinmed.edu
|
Service list |
► RIA and ELISA list (18) | |||
Name | Description | Price | |
---|---|---|---|
A2 Macroglobulin ELISA, Human | Inquire | ||
CK 18 (M65) ELISA, Human | Inquire | ||
CK 18 Frag (M30) ELISA, Human | Inquire | ||
DHEAS ELISA, Human | Inquire | ||
Follicle Stimulating Hormone, human |
FSH ELISA Lab requires 60ul serum |
Internal
$12.57
each
External $25.14 each External Affiliate $15.71 each |
|
Hyaluronic Acid ELISA, Human | Inquire | ||
IL-1 beta, high sensitivity, Human ELISA |
ELISA, Human Lab requires 210ul serum/plasma |
Internal
$23.37
each
External $46.75 each External Affiliate $29.22 each |
|
Insulin, rodent Chemiluminescence ELISA |
Lab requires 15ul Serum/Plasma |
Internal
$19.23
each
External $38.47 each External Affiliate $24.04 each |
|
Leptin Receptor, Human ELISA | Inquire | ||
Luteinizing Hormone (LH) ELISA |
Lab requires 60ul serum |
Internal
$12.57
each
External $25.14 each External Affiliate $15.71 each |
|
NGAL ELISA |
The neutrofil gelatinase-associated lipocalin (NGAL) ELISA has been validated for human urine. Lab requires 25ul urine |
Inquire | |
Pepsinogen I, Human ELISA | Inquire | ||
Pepsinogen II, Human ELISA | Inquire | ||
Proinsulin, Human RIA | Inquire | ||
sRAGE, Human ELISA |
Soluble form of receptor for advanced glycation end-products. Serum or plasma - 125 µL needed |
Internal
$17.85
each
External $35.71 each External Affiliate $22.32 each |
|
TIMP-1, Human ELISA | Inquire | ||
Tissue Factor, Human ELISA | Inquire | ||
VEGF, Human ELISA | Inquire | ||
► Sample Processing (7) | |||
Name | Description | Price | |
CSF | Inquire | ||
CSF Pellet | Inquire | ||
CSF SUP | Inquire | ||
External Sample Processing | Inquire | ||
Industry Sample shipping prep | Inquire | ||
Red blood cell pellet |
Collected after centrifugation and removal of supernatant. |
Internal
$0.50
each
External $1.00 each External Affiliate $0.63 each |
|
Sample tracking |
Internal
$0.40
each
External $1.00 each External Affiliate $0.63 each |
||
► Other Services (2) | |||
Name | Description | Price | |
Protease inhibitor tubes |
DRC Member (External)
$4.00
each
Internal $4.00 each External $8.00 each External Affiliate $8.00 each |
||
Short-term storage |
Per participant for industry-sponsored studies |
Inquire | |
► Archived (3) | |||
Name | Description | Price | |
Androstenedione, LCMS | Inquire | ||
Short term storage- non industry/ per vial | Inquire | ||
Testosterone, LCMS | Inquire |